Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | SLC22A18 |
| Gene Name: | SLC22A18 |
| Protein Full Name: | Solute carrier family 22 member 18 |
| Alias: | Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein;Efflux transporter-like protein;Imprinted multi-membrane-spanning polyspecific transporter-related protein 1;Organic cation transporter-like protein 2;Solute carrier family 22 member 1-like;Tumor-suppressing STF cDNA 5 protein;Tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein;p45-Beckwith-Wiedemann region 1 A |
| Mass (Da): | 44846 |
| Number AA: | 424 |
| UniProt ID: | Q96BI1 |
| Locus ID: | 5002 |
| COSMIC ID: | SLC22A18 |
| Gene location on chromosome: | 11p15.5 |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.3 |
| Normal role description: | Transporter - for organic cations. May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney. |
| Commentary on involvement of protein in cancer: | May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney. |