Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | PPP1R14B |
| Gene Name: | PPP1R14B |
| Protein Full Name: | Protein phosphatase 1 regulatory subunit 14B |
| Alias: | PHI-1; Phospholipase C beta 3 neighbouring gene protein; Phospholipase C beta-3 neighboring gene protein; PLCB3N; PNG; PP14B; Protein phosphatase 1, regulatory (inhibitor) subunit 14B; SOM172 |
| Mass (Da): | 15911 |
| Number AA: | 147 |
| UniProt ID: | Q96C90 |
| Locus ID: | 26472 |
| COSMIC ID: | PPP1R14B |
| Gene location on chromosome: | 11q13.1 |
| Number of cancer specimens: | 20149 |
| Percent of cancer specimens with mutations: | 0.12 |
| Normal role description: | PPP1R14B is a protein-serine/threonine phosphatase regulatory protein. Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated. NON-ANOTATED GENE |