Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: HIC2
Gene Name: HIC2
Protein Full Name: Hypermethylated in cancer 2 protein
Alias: HIC1-related gene on chromosome 22 protein;Hic-3;Zinc finger and BTB domain-containing protein 30
Mass (Da): 66156
Number AA: 615
UniProt ID: Q96JB3
Locus ID: 23119
COSMIC ID: HIC2
Gene location on chromosome: 22q11.21
Number of cancer specimens: 19813
Percent of cancer specimens with mutations: 0.54
Normal role description: Transcriptional repressor.


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