Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | CNDP2 |
| Gene Name: | CNDP2 |
| Protein Full Name: | Cytosolic non-specific dipeptidase |
| Alias: | CN2; CNDP dipeptidase 2; CNDP dipeptidase 2 (metallopeptidase M20 family); CPGL; Cytosolic nonspecific dipeptidase; Glutamate carboxypeptidase-like 1; PEPA; Peptidase A |
| Mass (Da): | 52878 |
| Number AA: | 475 |
| UniProt ID: | Q96KP4 |
| Locus ID: | 55748 |
| COSMIC ID: | CNDP2 |
| Gene location on chromosome: | 18q22.3 |
| Number of cancer specimens: | 19626 |
| Percent of cancer specimens with mutations: | 0.54 |
| Commentary on involvement of protein in cancer: | Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Isoform 2 may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells. |