Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | JAKMIP1 |
| Gene Name: | JAKMIP1 |
| Protein Full Name: | Janus kinase and microtubule-interacting protein 1 |
| Alias: | Gababrbp; JAMIP1; Janus kinase and microtubule interacting protein 1; Marlin1 |
| Mass (Da): | 97436 |
| Number AA: | 626 |
| UniProt ID: | Q96N16 |
| Locus ID: | 152789 |
| COSMIC ID: | JAKMIP1 |
| Gene location on chromosome: | 4p16.1 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 19780 |
| Percent of cancer specimens with mutations: | 1.16 |
| Normal role description: | Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signalling and regulate microtubule cytoskeleton rearrangements. Role in oncogenesis unclear |