Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | MAGI1 |
| Gene Name: | MAGI1 |
| Protein Full Name: | Membrane-associated guanylate kinase, WW and PDZ d |
| Alias: | AIP3; Atrophin-1-interacting 3; Atrophin-1-interacting protein 3; BAI1-associated 1; BAI1-associated protein 1; BAIAP1; BAP1; BAP-1; MAGI-1; Membrane associated guanylate kinase, WW and PDZ domain containing 1; Membrane-associated guanylate kinase inverted 1; Membrane-associated guanylate kinase, WW and PDZ domain-containing 1; TNRC19; Trinucleotide repeat-containing gene 19; Trinucleotide repeat-containing gene 19 protein; WW domain-containing protein 3; WWP3 |
| Mass (Da): | 164581 |
| Number AA: | 1491 |
| UniProt ID: | Q96QZ7 |
| Locus ID: | 9223 |
| COSMIC ID: | MAGI1 |
| Gene location on chromosome: | 3p14.1 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 20239 |
| Percent of cancer specimens with mutations: | 1.21 |
| Normal role description: | Suggested to play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ACCN3 currents by modulating its expression at the cell surface. |