Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | ORAI2 |
| Gene Name: | ORAI2 |
| Protein Full Name: | Protein orai-2 |
| Alias: | CAP-binding protein complex-interacting protein 2;Transmembrane protein 142B |
| Mass (Da): | 28570 |
| Number AA: | 254 |
| UniProt ID: | Q96SN7 |
| Locus ID: | 80228 |
| COSMIC ID: | ORAI2 |
| Gene location on chromosome: | 7q22. |
| Number of cancer specimens: | 19784 |
| Percent of cancer specimens with mutations: | 0.32 |
| Commentary on involvement of protein in cancer: | Ca2+ release-activated Ca2+-like (CRAC-like) channel subunit which mediates Ca2+ influx and increase in Ca2+-selective current by synergy with the Ca2+ sensor, STIM1. |