Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | FEV |
| Gene Name: | FEV |
| Protein Full Name: | Protein FEV |
| Alias: | Fifth Ewing variant protein;PC12 ETS domain-containing transcription factor 1 |
| Mass (Da): | 25030 |
| Number AA: | 238 |
| UniProt ID: | Q99581 |
| Locus ID: | 54738 |
| COSMIC ID: | FEV |
| Gene location on chromosome: | 2q36 |
| Number of cancer specimens: | 20545 |
| Percent of cancer specimens with mutations: | 0.13 |
| Commentary on involvement of protein in cancer: | Functions as a transcriptional regulator. According to Ref.5, it functions as a transcriptional repressor. Functions in the differentiation and the maintenance of the central serotonergic neurons. May play a role in cell growth. |