Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: Smad5
Gene Name: SMAD5
Protein Full Name: Mothers against decapentaplegic homolog 5
Alias: Dwarfin-C; Dwfc; Dwf-C; JV5-1; MADH5; Mothers against decapentaplegic homolog 5: SMAD 5: hSmad5: JV5-1; Mothers against DPP homolog 5; MSMAD5; SMAD 5; SMAD family member 5
Mass (Da): 52258
Number AA: 465
UniProt ID: Q99717
Locus ID: 4090
COSMIC ID: SMAD5
Gene location on chromosome: 5q31.1
Number of cancer specimens: 19535
Percent of cancer specimens with mutations: 0.02


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