Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | BRIP1 |
| Gene Name: | BRIP1 |
| Protein Full Name: | Fanconi anemia group J protein |
| Alias: | BACH1; BRCA1 interacting protein C-terminal helicase 1; BRCA1-binding helicase-like protein BACH1; BRCA1-interacting protein 1; FANCJ; FLJ90232; HGNC:20473; OF |
| Mass (Da): | 140878 |
| Number AA: | 1249 |
| UniProt ID: | Q9BX63 |
| Locus ID: | 83990 |
| COSMIC ID: | BRIP1 |
| Gene location on chromosome: | 17q22.2 |
| Number of cancer specimens: | 20444 |
| Percent of cancer specimens with mutations: | 0.95 |
| Normal role description: | RNA helicases-RecQ DEAH family. The protein functions in double-strand DNA break repair in concert with BRCA1. |