Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | MUC13 |
| Gene Name: | MUC13 |
| Protein Full Name: | Mucin-13 |
| Alias: | DRCC1; FLJ20063; mucin 13; mucin 13, cell surface associated; mucin 13, epithelial transmembrane |
| Mass (Da): | 54604 |
| Number AA: | 512 |
| UniProt ID: | Q9H3R2 |
| Locus ID: | 56667 |
| COSMIC ID: | MUC13 |
| Gene location on chromosome: | 3q21.2 |
| Cancer protein type: | OP |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 7056 |
| Percent of cancer specimens with mutations: | 0.54 |
| Normal role description: | Mucins protect the surface of epithelial tissues from noxious and toxic substances and form a physical barrier from the extracelullar environment. Various SNPs have been identified, although their significance is unclear. Aberrant and overexpression associated with ovarian, colon and gastric cancers. |