Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | ZMAT3 |
| Gene Name: | ZMAT3 |
| Protein Full Name: | Zinc finger matrin-type protein 3 |
| Alias: | Zinc finger protein WIG-1;p53-activated gene 608 protein |
| Mass (Da): | 32059 |
| Number AA: | 289 |
| UniProt ID: | Q9HA38 |
| Locus ID: | 64393 |
| COSMIC ID: | ZMAT3 |
| Gene location on chromosome: | 3q26.32 |
| Number of cancer specimens: | 19717 |
| Percent of cancer specimens with mutations: | 0.32 |
| Commentary on involvement of protein in cancer: | Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus. |