Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | PATZ1 |
| Gene Name: | PATZ1 |
| Protein Full Name: | POZ-, AT hook-, and zinc finger-containing protein |
| Alias: | BTB-POZ domain zinc finger transcription factor; DJ400N23; MAZR; PATZ; POZ (BTB) and AT hook containing zinc finger 1; Protein kinase A RI subunit alpha-associated protein; RIAZ; ZBTB19; Zinc finger and BTB domain-containing protein 19; Zinc finger protein 278; Zinc finger sarcoma gene protein; ZNF278; ZSG |
| Mass (Da): | 74060 |
| Number AA: | 687 |
| UniProt ID: | Q9HBE1 |
| Locus ID: | 23598 |
| COSMIC ID: | PATZ1 |
| Gene location on chromosome: | 22q12.2 |
| Cancer protein type: | NA |
| Effect of cancer mutation on protein: | NA |
| Effect of active protein on cancer: | NA |
| Number of cancer specimens: | 20081 |
| Percent of cancer specimens with mutations: | 0.35 |
| Normal role description: | NA |
| Commentary on involvement of protein in cancer: | Note: in small round cell sarcoma, PATZ1 is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12)). |