Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | KIAA1632 |
| Gene Name: | KIAA1632 |
| Protein Full Name: | UPF0493 protein KIAA1632 |
| Mass (Da): | 292481 |
| Number AA: | 2579 |
| UniProt ID: | Q9HCE0 |
| Locus ID: | 57724 |
| COSMIC ID: | KIAA1632 |
| Gene location on chromosome: | 18q12.3 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 582 |
| Percent of cancer specimens with mutations: | 1.7182130584 |
| Normal role description: | KIAA1632 may play a role in the degradation step of the autophagy pathway. |
| Commentary on involvement of protein in cancer: | 2/468 CNS-, and 1/1 pharyngeal tumour samples were also mutated. Only 2 ovarian-, 1 oral- and 1 melanoma sample were included in Sanger COSMIC. |