Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: FGF22
Gene Name: FGF22
Protein Full Name: Fibroblast growth factor 22
Alias: UNQ2500/PRO5800
Mass (Da): 19663
Number AA: 170
UniProt ID: Q9HCT0
Locus ID: 27006
COSMIC ID: FGF22
Gene location on chromosome: 19p13.3
Number of cancer specimens: 20057
Percent of cancer specimens with mutations: 0.11
Commentary on involvement of protein in cancer: Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development.


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