Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | BCL2L10 |
| Gene Name: | BCL2L10 |
| Protein Full Name: | Bcl-2-like protein 10 |
| Alias: | Anti-apoptotic protein NrH;Apoptosis regulator Bcl-B |
| Mass (Da): | 21973 |
| Number AA: | 194 |
| UniProt ID: | Q9HD36 |
| Locus ID: | 10017 |
| COSMIC ID: | BCL2L10 |
| Gene location on chromosome: | 15q21.2 |
| Number of cancer specimens: | 19718 |
| Percent of cancer specimens with mutations: | 0.12 |
| Normal role description: | Promotes cell survival and inhibits apoptosis. Appears to block function of caspases 3 and 8. However in other cell systems BCL2L10 promotes cell death. |