Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | SEMA4B |
| Gene Name: | SEMA4B |
| Protein Full Name: | Semaphorin-4B |
| Alias: | KIAA1745; MGC131831; SEM4B; Sema domain, immunoglobulin domain (Ig) transmembrane domain (TM) and short cytoplasmic domain,; Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B; Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4B; SEMAC; Semaphorin 4B; Semaphorin-4B; SemC |
| Mass (Da): | 92193 |
| Number AA: | 832 |
| UniProt ID: | Q9NPR2 |
| Locus ID: | 10509 |
| COSMIC ID: | SEMA4B |
| Gene location on chromosome: | 15q25 |
| Number of cancer specimens: | 19850 |
| Percent of cancer specimens with mutations: | 0.47 |
| Commentary on involvement of protein in cancer: | Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons |