Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | ABCB10 |
| Gene Name: | ABCB10 |
| Protein Full Name: | ATP-binding cassette sub-family B member 10, mitoc |
| Alias: | ATP-binding cassette transporter 10;Mitochondrial ATP-binding cassette 2 |
| Number AA: | 738 |
| UniProt ID: | Q9NRK6 |
| Locus ID: | 23456 |
| COSMIC ID: | ABCB10 |
| Gene location on chromosome: | 1q42 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 19689 |
| Percent of cancer specimens with mutations: | 0.52 |
| Normal role description: | ABCB10 is suspected to mediate critical mitochondrial transport functions related to heme biosynthesis. It is a mitochondrion inner membrane, multi-pass membrane protein. The precise function of this mitochondrial protein is unknown. |