Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | PKDREJ |
| Gene Name: | PKDREJ |
| Protein Full Name: | Polycystic kidney disease and receptor for egg jel |
| Alias: | PKD and REJ homolog; PKDRE; polycystic kidney disease (polycystin) and REJ (sperm receptor for egg jelly, sea urchin); polycystic kidney disease and receptor for egg jelly related protein |
| Mass (Da): | 255450 |
| Number AA: | 2253 |
| UniProt ID: | Q9NTG1 |
| Locus ID: | 10343 |
| COSMIC ID: | PKDREJ |
| Gene location on chromosome: | 22q13.31 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 19689 |
| Percent of cancer specimens with mutations: | 1.62 |
| Normal role description: | PKDREJ may have a role in facilitating reproduction. It may be involved in initiating acrosome reaction of sperm by generating a calcium channel. |