Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | TEX10 |
| Gene Name: | TEX10 |
| Protein Full Name: | Testis-expressed sequence 10 protein |
| Alias: | L18, Nbla10363 |
| Mass (Da): | 105674 |
| Number AA: | 929 |
| UniProt ID: | Q9NXF1 |
| Locus ID: | 54881 |
| COSMIC ID: | TEX10 |
| Gene location on chromosome: | 9q31.1 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.74 |
| Normal role description: | Component of some MLL1/MLL complex, at least composed of the core components MLL, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components C17orf49, CHD8, E2F6, HSP70, IN80C, KIAA1267, LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. (uniprot). Role in oncogenesis unclear |