Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: RGL1
Gene Name: RGL1
Protein Full Name: Ral guanine nucleotide dissociation stimulator-lik
Alias: RalGDS-like; RalGDS-like 1; RGL
Mass (Da): 86701
Number AA: 768
UniProt ID: Q9NZL6
Locus ID: 23179
COSMIC ID: RGL1
Gene location on chromosome: 1q25.3
Cancer protein type: OP
Effect of cancer mutation on protein: UNCLEAR
Effect of active protein on cancer: UNCLEAR
Number of cancer specimens: 20213
Percent of cancer specimens with mutations: 0.73
Normal role description: G Protein regulator - Dissociation stimulator. Probable guanine nucleotide exchange factor. Interacts with Ras.


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