Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | AFF4 |
| Gene Name: | AFF4 |
| Protein Full Name: | ISOFORM 1 OF AF4/FMR2 FAMILY MEMBER 4. |
| Alias: | AF4/FMR2 family member 4: ALL1-fused gene from chromosome 5q31: Major CDK9 elongation factor-associated protein: AF4/FMR2 family member 4: ALL1-fused gene from chromosome 5q31: Major CDK9 elongation factor-associated protein; ALL1-fused gene from chromosome 5q31 |
| Mass (Da): | 127459 |
| Number AA: | 1163 |
| UniProt ID: | Q9UHB7 |
| Locus ID: | 27125 |
| COSMIC ID: | AFF4 |
| Gene location on chromosome: | 5q31 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 19805 |
| Percent of cancer specimens with mutations: | 0.95 |
| Normal role description: | Potential role in transcription regulation. |