Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | ARHGAP26 |
| Gene Name: | ARHGAP26 |
| Protein Full Name: | Rho GTPase-activating protein 26 |
| Alias: | Graf; GTPase regulator associated with focal adhesion kinase; GTPase regulator associated with focal adhesion kinase pp125(FAK); GTPase regulator associated with the focal adhesion kinase pp125; KIAA0621; Oligophrenin-1 like protein; Oligophrenin-1-like protein; OPHN1L; OPHN1L1; RHG26; Rho GTPase activating protein 26; RhoGAP 26; Rho-GTPase-activating protein 26; Rho-type GTPase-activating protein 26 |
| Mass (Da): | 92235 |
| Number AA: | 814 |
| UniProt ID: | Q9UNA1 |
| Locus ID: | 23092 |
| COSMIC ID: | ARHGAP26 |
| Gene location on chromosome: | 5q31 |
| Cancer protein type: | TSP |
| Effect of cancer mutation on protein: | LOSS |
| Effect of active protein on cancer: | INHIBITS |
| Number of cancer specimens: | 20976 |
| Percent of cancer specimens with mutations: | 0.57 |
| Normal role description: | Act as a GTPase activating protein for active Rho-GTP. Negative regulator of RhoA. |