Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: PPIE
Gene Name: PPIE
Protein Full Name: Peptidyl-prolyl cis-trans isomerase E
Alias: Cyclophilin 33; Cyclophilin E; CYP33; CYP-33; MGC111222; MGC3736; Peptidylprolyl isomerase E; Peptidylprolyl isomerase E, isoform 1; PPIase E; Rotamase E
Mass (Da): 33431
Number AA: 301
UniProt ID: Q9UNP9
Locus ID: 10450
COSMIC ID: PPIE
Gene location on chromosome: 1p32*
Cancer protein type: NA
Effect of cancer mutation on protein: NA
Effect of active protein on cancer: NA
Number of cancer specimens: 19625
Percent of cancer specimens with mutations: 0.2
Normal role description: NA
Commentary on involvement of protein in cancer: *chromosomal location = 1p34.2 according to Atlas of Genetic Oncology, but 1p32 according to NCBI gene & OMIM


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