Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: DIP2C
Gene Name: DIP2C
Protein Full Name: Disco-interacting protein 2 homologue C
Alias: DIP2 disco-interacting protein 2C
Mass (Da): 170767
Number AA: 1556
UniProt ID: Q9Y2E4
Locus ID: 22982
COSMIC ID: DIP2C
Gene location on chromosome: 10p15.3
Cancer protein type: UNCLEAR
Effect of cancer mutation on protein: UNCLEAR
Effect of active protein on cancer: UNCLEAR
Number of cancer specimens: 19798
Percent of cancer specimens with mutations: 1.57
Mutations observed as inherited: NA
Found in amplified chromosomal regions in human cancers: NA
Deregulated in translocations: NA
Deregulated by viral insertion: NA
Transduced into viral genome: NA
Gene undergoes hypermethylation: NA
Normal role description: DIP2C is a nuclear protein that can bind to the transcription factor DISCO.
Commentary on involvement of protein in cancer: no entry in AGO


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