Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: KLK4
Gene Name: KLK4
Protein Full Name: Kallikrein-4
Alias: Enamel matrix serine proteinase 1;Kallikrein-like protein 1;Prostase;Serine protease 17
Mass (Da): 27023
Number AA: 254
UniProt ID: Q9Y5K2
Locus ID: 9622
COSMIC ID: KLK4
Gene location on chromosome: 19q13.33
Cancer protein type: TSP
Effect of cancer mutation on protein: LOSS
Effect of active protein on cancer: PROMOTES
Number of cancer specimens: 19719
Percent of cancer specimens with mutations: 0.47
Normal role description: Serine protease.


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