Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | ETV7 |
| Gene Name: | ETV7 |
| Protein Full Name: | Transcription factor ETV7 |
| Alias: | Ets transcription factor tel-2a; Ets transcription factor tel-2b; Ets transcription factor tel-2b variant; Ets transcription factor tel-2c; Ets transcription factor tel-2d; Ets transcription factor tel2e; Ets transcription factor tel2f; Ets variant gene 7 (tel2 oncogene); Etv7; Tel2; Tel-2; Telb; Telb protein; Transcription factor ets |
| Mass (Da): | 38998 |
| Number AA: | 341 |
| UniProt ID: | Q9Y603 |
| Locus ID: | 51513 |
| COSMIC ID: | ETV7 |
| Gene location on chromosome: | 6p21 |
| Number of cancer specimens: | 19905 |
| Percent of cancer specimens with mutations: | 0.3 |
| Commentary on involvement of protein in cancer: | Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity. |