Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | CDH10 |
| Gene Name: | CDH10 |
| Protein Full Name: | Cadherin-10 |
| Alias: | CAD10; Cadherin 10, type 2; Cadherin-10; T2-cadherin |
| Mass (Da): | 88451 |
| Number AA: | 788 |
| UniProt ID: | Q9Y6N8 |
| Locus ID: | 1008 |
| COSMIC ID: | CDH10 |
| Gene location on chromosome: | 5p14.2-p14.1 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 19904 |
| Percent of cancer specimens with mutations: | 2.51 |
| Normal role description: | CDH10 encodes for an integral membrane protein that mediates calcium-dependent cell-cell adhesion,by preferentially interacting with themselves in a homophilic manner in connecting cells, and may therefore contribute to the sorting of heterogeneous cell types. |